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 Post subject: Coat color genetics
 Post Posted: Mon Nov 24, 2008 12:09 pm 
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Joined: Sat Sep 27, 2008 10:27 am
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Location: SoCal
Since people are always so curious about the Blue Lacy coloring, here are some links to a few of the best canine color genetics sites and a quick explanation of how they work in Lacys.

Saying a Lacy carries a "blue gene" isn't exactly accurate. The Lacy colors come from the melanophilin (MLPH) gene. Black dogs are eumelanin pigmented, red dogs are phaeomelanin pigmented, and tri-color dogs have a combination of eumelanin and phaeomelanin pigments. What Lacys carry is a dilution gene that applies itself to all colors. The d/d genotype dilutes eumelanin to blue and phaeomelanin to light red, thus producing the three coat varieties we see in Lacys.

The white spotting is a little more confusing. White is controlled by the S loci, S denotes a solid color gene and s^i is an Irish spotted gene, and it is still unclear how these determine Lacy-type markings. An S/S dog can still have white on their toes, tail tip or a small area of the chest that is caused by incomplete melanocyte migration during fetal development. New studies have shown the rate of melanocyte migration may be inherited, so perhaps many Lacys are S/S but display minimal white spotting due to genetically slower pigmentation distribution during embryogenesis. Unmodified full Irish spotting, s^i/s^i, would result in excessive white markings that are considered a serious breed fault, but S/s^i could tone down full Irish marking into an acceptable amount of white on Lacys. It is also possible that Lacys have an additional modifier that controls the extent of Irish spotting, so that s^i/s^i dogs could still display minimal markings if the modifier is present. Until more is understood about the S loci, breeders will have to carefully study the presence of white in bloodlines to make proper breeding decisions.

http://homepage.usask.ca/~schmutz/dogcolors.html
http://bowlingsite.mcf.com/GENETICS/ColorGen.html
http://www.biomedcentral.com/1471-2156/6/34

_________________
"You must be a very small minority no matter who you hang around with. Maybe you should start a magazine, Vegetarian Hog Dogging Monthly, find some like-minded individuals."
- Inspiration for my next project from TBH

True Blue Lacys: http://www.truebluelacys.com
More Lacy Pics: http://www.flickr.com/photos/julieanna/sets/72157605027566732/


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 Post subject: Re: Coat color genetics
 Post Posted: Tue Feb 03, 2009 4:08 pm 
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Joined: Thu Dec 25, 2008 1:28 am
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Location: Bel Aire, KS
Ok, so in theory, the Lacy breed could be black or always carry the color black?


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